Simplex Bone Cement

Confidence, Choice and Performance.

With evidence from literature showing that bone cement choices may affect in vivo device fixation,1,2 your bone cement selection cannot be taken lightly.

Trust and History

Trust and History

With over 50 years10,11,12 of history, 600+ published studies13 and as the top-selling bone cement in the world,14 you can trust Stryker and the Simplex family of bone cements for clinically backed fixation, relevant handling and antibiotic choice.


Handling Choices and Fixation You Can Trust

Handling Choices and Fixation You Can Trust

  • The option of both medium dual-phase, and high viscosity bone cements.
  • Viscosity choice without compromising depth of intrusion.
  • Simplex P and Simplex HV both achieve greater than the studies recommended 4mm depth of cement penetration into cancellous bone. 3,4
Antibiotic Options

Antibiotic Options

  • The Simplex family offers both the greater activity of Tobramycin5 and the value of Gentamicin.
  • Antibiotic choices with comparable strength6,7,8 and with dependable antibiotic elution.6,9
Manufacturing quality

Manufacturing quality

Allows batch mixing

  • Predictable working time
  • Desirable handling characteristics

Commercially blended antibiotic demonstrates a more consistent mix and approximately 50% increase in strength over hand-blended antibiotic cement15

Extra Resources

Extra Resources

  1. TerBush M, Miller MA, Mann KA. Interface Micromechanics are Similar for Cemented TKR and THR Following In-Vivo Service. ORS 2013 Annual Meeting. Poster No: 1079.
  2. Gebert de Uhlenbrock A, Püschel V, Püschel K, Morlock MM, Bishop NE. Influence of time in-situ and implant type on fixation strength of cemented tibial trays — A post mortem retrieval analysis. Clinical Biomechanics 27. 929–935. 2011.
  3. Noble and Swarts, Penetration of Acrylic Bone Cements Into Cancellous Bone, Acta Orth Scand 1983; 54: 566-573.
  4. Askew MJ, Steege JW, Lewis JL, et al. Effect of cement pressure and bone strength on polymethylmethacrylate fixation. J Orthop Res. 1983, Issue 4, 412- 420.
  5. Scott CP, Higham PA, Dumbleton JH. Effectiveness of bone cement containing tobramycin: An in vitro susceptibility of 99 organisms found in infected joint arthroplasty. J Bone Joint Surgery (Br). 1999; 81-B:440-443.
  6. He S, Mulvihill H, et al. Comparative Handling, Intrusion and Antibiotic Elution Characteristics of a New, High Viscosity Bone Cement. Orthopedics Today Hawaii Conference. 2013.
  7. Stryker RD Report 01-044.
  8. Stryker RD Report 01-032.
  9. Nijhof M, Dhert W, Tillman P, Verbout A, Fleer A. Release of tobramycin-containing bone cement in bone serum of rabbits. J Mat Sci Mat Med. 1997; 8(12): 342-353.
  10. Gill G, Joshi A. Long-term results of Kinematic Condylar knee replacement. J Bone Joint Surg [Br] 2001;83-B:355-8.
  11. Ling R, Charity J, Lee C, Whitehouse S, Timperley A, Gie G. The Long-Term Results of the Original Exeter Polished Cemented Femoral Component The Journal of Arthroplasty Vol. 24 No. 4 2009.
  12. Smith, D. The genesis and evolution of acrylic bone cement. Orthop Clin of N Am 36 (2005) 1-10.
  13. Pubmed search, Nov. 2011.
  15. DeLuise M, Scott C. Addition of hand-blended generic tobramycin in bone cement: effect on mechanical strength. Orthopedics. Dec 2004, Vol. 27 (12): 1289-1291.
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